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KMID : 0191120220370360270
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Journal of Korean Medical Science
2022 Volume.37 No. 36 p.270 ~ p.270
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Annual Case Volume and One-Year Mortality for Endovascular Treatment in Acute Ischemic Stroke
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Kim Jun-Yup
Kang Ji-Hoon
Kim Beom-Joon
Kim Seong-Eun
Kim Do-Yeon
Lee Keon-Joo
Park Hong-Kyun
Cho Yong-Jin
Park Jong-Moo
Lee Kyung-Bok
Cha Jae-Kwan
Lee Ji-Sung
Lee June-Young
Yang Ki-Hwa
Hong Ock-Ran
Shin Ji-Hyeon
Park Jung-Hyun
Gorelick Philip B.
Bae Hee-Joon
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Abstract
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Background: The association between endovascular treatment (EVT) case volume per hospital and clinical outcomes has been reported, but the exact volume threshold has not been determined. This study aimed to examine the case volume threshold in this context.
Methods: National audit data on the quality of acute stroke care in patients admitted via emergency department, within 7 days of onset, in hospitals that treated ≥ 10 stroke cases during the audit period were analyzed. Ischemic stroke cases treated with EVT during the last three audits (2013, 2014, and 2016) were selected for the analysis. Annual EVT case volume per hospital was estimated and analyzed as a continuous and a categorical variable (in quartiles). The primary outcome measure was 1-year mortality as a surrogate of 3-month functional outcome. As post-hoc sensitivity analysis, replication of the study results was examined using the 2018 audit data.
Results: We analyzed 1,746 ischemic stroke cases treated with EVT in 120 acute care hospitals. The median annual EVT case volume was 12.0 cases per hospital, and mortality rates at 1 month, 3 months, and 1 year were 12.7%, 16.6%, and 23.3%, respectively. Q3 and Q4 had 33% lower odds of 1-year mortality than Q1. Adjustments were made for predetermined confounders. Annual EVT case volume cut-off value for 1-year mortality was 15 cases per year (P < 0.02). The same cut-off value was replicated in the sensitivity analysis.
Conclusion: Annual EVT case volume was associated with 1-year mortality. The volume threshold per hospital was 15 cases per year.
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KEYWORD
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Endovascular Treatment, Acute Stroke, Clinical Outcomes, Volume Threshold
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